Most published trials are underpowered to detect the infection rate following medical management. The MIST trial24 (Miscarriage Treatment Trial) reported an infection rate of 2% at 14 days (3% at 8 weeks) based on clinical assessment parameters. The rate of infection was similar to that found in the expectant and surgical groups. A similar infection rate of 3% was reported in a retrospective observational study25 and in randomized controlled trials.5,11,12
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